CD8 anticorps

N° du produit ABIN316755

Cet anticorps Souris Monoclonal détecte spécifiquement CD8 dans IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CD8 anticorps (ABIN316755)

Antigène: CD8

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD8 est non-conjugé

Application: Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 4B11

Détail du produit anti-CD8 anticorps

Specificité: This antibody recognizes the Human CD8 cell surface antigen, a 32 kDa glycoprotein expressed by the cytotoxic/suppressor subset of T-cells and weakly by NK cells. Clone 4B11 has been reported as being suitable for use in Western blotting. AM05530SU-N is recommended for this purpose.

Attributs du produit: Synonyms: T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain

Immunogène: Synthetic peptide derived from CD8 alpha chain sequence.

Isotype: IgG2b

Information d'application

Indications d'application: Immunohistochemistry on Frozen Sections: 1/20-1/40. Immunohistochemistry on paraffin sections: 1/20-1/40. This product requires antigenretrieval using heat treatment prior to staining of paraffin sections.1 mM EDTA pH 8.0 isrecommended for this purpose. Positive Control Tissue: Human Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with 1 mL distilled water.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one monthor (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD8

Antigène: CD8

Autre désignation: CD8

Sujet: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

ID gène: 925

UniProt: P01732