This antibody is specific for the C-terminal variant of Human CDw92 (isoform 3), also known as CTL1. Clone VIM-15b is reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells (Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10.
Attributs du produit
Synonyms: CDw92, CTL1, Choline transporter-like protein 1, Solute carrier family 44 member 1
Purification
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
SLC44A1
Reactivité: Humain
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Flow Cytometry: 1/50 - 1/200. Immunohistochemistry on frozen sections. Immunoprecipitation. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS, pH 7.4, 0.09 % Sodium Azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by
Date de péremption
12 months
Antigène
SLC44A1
(Solute Carrier Family 44, Member 1 (SLC44A1))
anticorps CD92, anticorps CDW92, anticorps CHTL1, anticorps CTL1, anticorps RP11-287A8.1, anticorps Cdw92, anticorps Ctl1, anticorps 2210409B22Rik, anticorps 4833416H08Rik, anticorps AW547365, anticorps SLC44A1, anticorps slc44a1, anticorps zgc:112201, anticorps ctl1, anticorps solute carrier family 44 member 1, anticorps solute carrier family 44, member 1, anticorps solute carrier family 44 (choline transporter), member 1a, anticorps solute carrier family 44 (choline transporter), member 1, anticorps choline transporter-like protein 1, anticorps Choline transporter-like protein 1, anticorps solute carrier family 44 (choline transporter), member 1 L homeolog, anticorps SLC44A1, anticorps Slc44a1, anticorps slc44a1a, anticorps slc44a1, anticorps LOC100404101, anticorps chtl-1, anticorps slc44a1.L
Sujet
CDw92 is a 70 kDa multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells. CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine.Synonyms: CDw92, CTL1, Choline transporter-like protein 1, Solute carrier family 44 member 1