SIGLEC7 anticorps
Aperçu rapide pour SIGLEC7 anticorps (ABIN316978)
Antigène
Voir toutes SIGLEC7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody is specific for CDw328.
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Attributs du produit
- Synonyms: Siglec-7, QA79 membrane protein, p75, D-siglec, CDw328, AIRM1, Sialic acid-binding Ig-likelectin 7, Adhesion inhibitory receptor molecule 1
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Purification
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
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Immunogène
- Monocyte-derived dendritic cells
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Isotype
- IgG1
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Indications d'application
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Flow Cytometry: 1/100 - 1/200. Immunohistochemistry on frozen sections: 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0mg/mL
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Buffer
- Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3)
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only. -
Date de péremption
- 12 months
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- SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
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Autre désignation
- CD328 / SIGLEC7
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Sujet
- CDw328 is a type I transmembrane glycoprotein and member of the Siglec (sialic acid binding Ig-like lectin) family, designated Siglec-7, originally identified as an inhibitory NK cell receptor (NKR) and negative regulator of NK activation, attributed to ITIM recruitment of SHP-1 phosphatase. CDw328 is expressed predominantly by natural killer cells (NK) and to a lesser extent by monocytes and granulocytes and, like Siglec-5 (CD170), has been shown to bind to sialylated ligands of targets through recognition of sialic acid in both the alpha-2,3- and alpha-2,6- glycosidic linkage.Synonyms: AIRM1, Adhesion inhibitory receptor molecule 1, CDw328, D-siglec, QA79 membrane protein, Sialic acid-binding Ig-like lectin 7, Siglec-7, p75
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ID gène
- 27036
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UniProt
- Q9Y286
Antigène
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