This antibody recognises SIRP gamma, a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily.
Attributs du produit
Synonyms: SIRP-beta-2, SIRP-b2, SIRPB2, SIRP gamma, Signal-regulatory protein gamma,Signal-regulatory protein beta-2, CD172 antigen-like family member B
Purification
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
SIRPG
Reactivité: Humain, Singe
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Flow Cytometry: 1/10. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0,1 mg/mL
Buffer
Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3) and 1 % Bovine Serum Albumin
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.
anticorps CD172g, anticorps SIRP-B2, anticorps SIRPB2, anticorps SIRPgamma, anticorps bA77C3.1, anticorps SIRPG, anticorps signal regulatory protein gamma, anticorps signal-regulatory protein gamma, anticorps SIRPG, anticorps LOC716034, anticorps LOC102138723
Sujet
SIRP gamma, also known as CD172g, is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. It is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.Synonyms: CD172 antigen-like family member B, SIRP gamma, SIRP-b2, SIRP-beta-2, SIRPB2, Signal-regulatory protein beta-2, Signal-regulatory protein gamma