NPPB anticorps (N-Term)
Aperçu rapide pour NPPB anticorps (N-Term) (ABIN317050)
Antigène
Voir toutes NPPB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-32, N-Term
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Specificité
- This antibody detects an epitope located at the C-terminal (amino acids 26-32) of the brain natriuretic peptide (BNP), a secreted protein which is a member of the natriuretic peptide family. This antibody also detects proBNP.
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Attributs du produit
- Synonyms: NPPB
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Purification
- Purified IgG prepared by affinity chromatography on Protein A
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Immunogène
- Human synthetic BNP.
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Isotype
- IgG1
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Indications d'application
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ELISA. Western Blot: detects a band of approximately 4 kDa when using synthetic BNP and a bandof 14 kDa when using recombinant proBNP. Immunoassay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0mg/mL
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Buffer
- Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3)
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by -
Date de péremption
- 12 months
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- NPPB (Natriuretic Peptides B (NPPB))
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Autre désignation
- Natriuretic Peptides B
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Sujet
- BNP is a cardiac hormone, which is synthesised as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation. BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure.Synonyms: NPPB
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ID gène
- 4879
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UniProt
- P16860
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Pathways
- Hormone Activity
Antigène
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