IL-10 anticorps

N° du produit ABIN317389

Cet anticorps Souris Monoclonal détecte spécifiquement IL-10 dans FACS, EIA, ELISpot et ELISA (Capture). Il présente une réactivité envers Boeuf (Vache), Cheval et Mouton.

Aperçu rapide pour IL-10 anticorps (ABIN317389)

Antigène: IL-10 (IL10) (Interleukin 10 (IL10))

Reactivité: Boeuf (Vache), Cheval, Mouton

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-10 est non-conjugé

Application: Flow Cytometry (FACS), Enzyme Immunoassay (EIA), ELISpot, ELISA (Capture)

Clone: CC318

Détail du produit anti-IL-10 anticorps

Specificité: This antibody recognizes IL-10. Clone CC318 has been shown not to inhibit the biological activity of IL-10.

Attributs du produit: Synonyms: IL-10, CSIF, TGIF, Cytokine synthesis inhibitory factor

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogène: Plasmid cDNA encoding bovine IL-10.

Isotype: IgG2b

Information d'application

Indications d'application: ELISA (capture): 5 μg/mL - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Soduim Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur IL-10

Antigène: IL-10 (IL10) (Interleukin 10 (IL10))

Autre désignation: Interleukin-10 / IL10

Sujet: Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Human IL10 is a non glycosylated polypeptide consisting of 178 amino acids. There is 73 % homology between the human and mouse IL10 proteins, however, the human IL10 acts on both human and mouse target cells, while the mouse IL10 has species specific activity. The cellular sources of IL10 are CD4+ T cells and T cell clones, thymocytes, B cells and B cell lymphomas, macrophages, mast cell lines and keratinocytes. IL10 will stimulate the growth of stem cells, mast cells and thymocytes. IL10 enhances cytotoxic T cell development, and costimulates B cell differentiation and immunoglobulin secretion. IL10 inhibits cytokine production by macrophages and suppresses macrophage class II MHC expression. The human IL10 gene is on human chromosome 1.Synonyms: CSIF, Cytokine synthesis inhibitory factor, IL-10, TGIF

ID gène: 281246

UniProt: P43480

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints