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Sialoadhesin/CD169 anticorps (FITC)

L’anticorps Rat Monoclonal anti-Sialoadhesin/CD169 a été validé pour FACS. Il convient pour détecter Sialoadhesin/CD169 dans des échantillons de Souris.
N° du produit ABIN317444

Aperçu rapide pour Sialoadhesin/CD169 anticorps (FITC) (ABIN317444)

Antigène

Voir toutes Sialoadhesin/CD169 (SIGLEC1) Anticorps
Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Reactivité

  • 53
  • 19
  • 18
  • 4
  • 3
Souris

Hôte

  • 33
  • 28
  • 12
  • 4
Rat

Clonalité

  • 40
  • 34
  • 1
Monoclonal

Conjugué

  • 33
  • 8
  • 7
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Sialoadhesin/CD169 est conjugé à/à la FITC

Application

  • 49
  • 42
  • 33
  • 16
  • 16
  • 15
  • 13
  • 13
  • 12
  • 10
  • 9
  • 8
  • 6
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Clone

3D6-112
  • Specificité

    This antibody recognizes Mouse CD169, a sialic acid binding site of sialoadhesin.

    Réactivité croisée (Details)

    Species reactivity (tested):Mouse.

    Attributs du produit

    Synonyms: Sialoadhesin, Siglec-1, Sialic acid-binding Ig-like lectin 1

    Purification

    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

    Immunogène

    Purified Sialoadhesin. Spleen cells from an immunised AO rat were fused with the cells of the Y3 rat myeloma cellline.

    Isotype

    IgG2a
  • Indications d'application

    Flow Cytometry: neat-1/5 (The Fc region of monoclonal antibodies may bindnon-specifically to cells expressing low affinity Fc receptors).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.09 % Sodium Azide, 1 % BSA

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    Date de péremption

    12 months
  • Antigène

    Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

    Autre désignation

    CD169 / SIGLEC1

    Sujet

    Two families of mammalian lectin like adhesion molecules have been shown to bind glycoconjugate ligands in a sialic acid dependent manner: the selectins and the sialoadhesins. The sialoadhesin family has 4 members: CD22, a B cell specific marker, myelin associated glycoprotein (MAG), which is expressed on oligodendrocytes and Schwann cells, CD33, a myeloid differentiation antigen, and sialoadhesin, which is expressed only by a subpopulation of tissue macrophages. Involved in cell-cell interactions, sialoadhesin is structurally related to the 3 other listed members of the sialoadhesin family. CD169 is a sialic acid binding site of sialoadhesin. CD169 is a macrophage receptor expressed on stromal macrophages in many tissues, particularly found in lymph nodes, bone marrow and spleen.Synonyms: Sialic acid-binding Ig-like lectin 1, Sialoadhesin, Siglec-1

    ID gène

    20612

    UniProt

    Q62230
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