CTSL1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
RB52889
unconjugated
Indications d'application
ELISA. Western blot: 1/1000-1/2000. Immunohistochemistry on Paraffin Sections: 5 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
1.0 mg/mL
Buffer
PBS, pH 7.4, containing 0.09 % Sodium Azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Date de péremption
12 months
Zheng, Chu, Chou, Gallati, Dier, Mirkin, Mousa, Rebbaa: "Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism." dans: American journal of physiology. Cell physiology, Vol. 296, Issue 1, pp. C65-74, (2009) (PubMed).
Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L can be induced by many different signaling events, including growth factor, secondary messenger and tumor promoters. Cathepsin L is translated as pre-procathepsin L, transferred through the Golgi apparatus as procathepsin L and then stored in lysosomes as mature cathepsin L.Synonyms: CTSL, CTSL1, Cathepsin-L1, MEP, Major excreted protein