Cathepsin L anticorps (AA 114-333)

N° du produit ABIN317508

Cet anticorps Souris Monoclonal détecte spécifiquement Cathepsin L dans WB, IHC (p) et EIA. Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.

Aperçu rapide pour Cathepsin L anticorps (AA 114-333) (ABIN317508)

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cathepsin L est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 2H7

Détail du produit anti-Cathepsin L anticorps

Épitope: AA 114-333

Specificité: The antibody recognizes Human Cathepsin L. Other species not tested.

Attributs du produit: Synonyms: CTSL1, CTSL, MEP, Cathepsin-L1, Major excreted protein

Purification: Protein-G affinity chromatography

Immunogène: Recombinant Human Cathepsin L (114-333 aa) purified from E. coli

Isotype: IgG2b

Information d'application

Indications d'application: ELISA. Western blot: 1/1000-1/2000. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Références pour anticorps anti-Cathepsin L (ABIN317508)

Zheng, Chu, Chou, Gallati, Dier, Mirkin, Mousa, Rebbaa: "Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism." dans: American journal of physiology. Cell physiology, Vol. 296, Issue 1, pp. C65-74, (2009) (PubMed).

Détails sur Cathepsin L

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Autre désignation: Cathepsin L1

Sujet: Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L can be induced by many different signaling events, including growth factor, secondary messenger and tumor promoters. Cathepsin L is translated as pre-procathepsin L, transferred through the Golgi apparatus as procathepsin L and then stored in lysosomes as mature cathepsin L.Synonyms: CTSL, CTSL1, Cathepsin-L1, MEP, Major excreted protein

ID gène: 1514

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades