MCHR2 anticorps

N° du produit ABIN317652

Détail du produit anti-MCHR2 anticorps

Antigène: MCHR2 (Melanin-Concentrating Hormone Receptor 2 (MCHR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCHR2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificité: This antibody detects endogenous levels of MCH-2R protein.(region surrounding Met332)

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/1000-1/5000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MCHR2

Antigène: MCHR2 (Melanin-Concentrating Hormone Receptor 2 (MCHR2))

Autre désignation: MCHR2 / GPR145 (MCHR2 Produits)

Synonymes: anticorps GPR145, anticorps GPRv17, anticorps MCH-2R, anticorps MCH-R2, anticorps MCH2, anticorps MCH2R, anticorps MCHR-2, anticorps SLT, anticorps melanin concentrating hormone receptor 2, anticorps MCHR2

Sujet: Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic neuropeptide,which is mainly expressed in the hypothalamus. MCH modulates feeding behavior, aggression, anxiety, arousal and reproductive function in mammals by controlling the release of luteinizing hormone (LH). The melanin-concentrating hormone receptor (MCHR, also designated SLC-1) is a glycosylated G-protein coupled receptor that migrates between 45-50 kDa on SDS-PAGE. MCHR mediates the effects of MCH through Gai and/or Gaq signaling and is expressed in several regions of the brain, including the cerebral cortex, amygdala, thalamus and hypothalamus. MCH and MCHR have also been implicated in stimulating leptin expression and secretion in adipocytes, which suggests that the melanin-concentrating hormone and its receptor may be potential targets for modulating obesity.Synonyms: G-protein coupled receptor 145, GPRv17, MCH receptor 2, MCH-2R, MCH-R2, MCHR-2, Melanin-concentrating hormone receptor 2, SLT

Poids moléculaire: approx. 39 kDa

ID gène: 84539

NCBI Accession: NP_001035269

UniProt: Q969V1