KCNJ11 anticorps

N° du produit ABIN317660

L’anticorps anti-KCNJ11 Polyclonal Lapin est utilisé pour la détection de KCNJ11 dans des échantillons de Humain et Souris. Il a été validé pour WB, IF et IHC (p).

Aperçu rapide pour KCNJ11 anticorps (ABIN317660)

Antigène: KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNJ11 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-KCNJ11 anticorps

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur KCNJ11

Antigène: KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))

Autre désignation: KCNJ11

Sujet: ATP-sensitive K+ channels play important roles in many cellular functions by coupling cell metabolism to electrical activity. KIR6.1 and KIR6.2 are members of the KIR (inwardly rectifying potassium channel) family of potassium channels. Inward rectifying K+ channels possess a greater tendency to allow potasium to flow into the cell rather than out of it. These channels comprise two subunits: a KIR6.0 subfamily component and a SUR component, which is a member of the ATP-binding cassette protein superfamily. Mutations in the gene coding for these channels are a cause of an autosomal recessive disorder characterized by unregulated insulin secretion. The amino-terminal and carboxyl-terminal domains of KIR channel subunits are both intracellular, and the two intracellular domains of KIR6.2 physically interact with each other.Synonyms: ATP-sensitive inward rectifier potassium channel 11, IKATP, Inward rectifier K+ channel Kir6.2, KCNJ11, Potassium channel, inwardly rectifying subfamily J member 11

Poids moléculaire: approx. 40 kDa

ID gène: 9606

UniProt: Q14654

Pathways: Negative Regulation of Hormone Secretion