CHRM1 anticorps

N° du produit ABIN317696

Détail du produit anti-CHRM1 anticorps

Antigène: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Reactivité: Rat, Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRM1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects endogenous levels of Muscarinic acetylcholine receptor M1 / mAChR M1 protein (region surrounding Arg336).

Purification: Affinity-chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CHRM1

Antigène: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Autre désignation: Muscarinic Acetylcholine Receptor M1 (CHRM1 Produits)

Synonymes: anticorps M1, anticorps CHRM1, anticorps HM1, anticorps M1R, anticorps mAChR, anticorps Chrm-1, anticorps cholinergic receptor muscarinic 1, anticorps cholinergic receptor, muscarinic 1, anticorps cholinergic receptor, muscarinic 1, CNS, anticorps CHRM1, anticorps Chrm1

Sujet: The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain.Synonyms: CHRM1, mAChR M1, mAChR-M1

Poids moléculaire: Approx. 50 kDa

ID gène: 1128

NCBI Accession: NP_000729

UniProt: P11229

Pathways: Synaptic Membrane