IP6K2 anticorps

N° du produit ABIN317720

Détail du produit anti-IP6K2 anticorps

Antigène: IP6K2 (Inositol Hexakisphosphate Kinase 2 (IP6K2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IP6K2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects endogenous levels of InsP6 kinase 2 / IP6K2 protein (region surrounding Leu188).

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity-chromatography

Information d'application

Indications d'application: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 15 mM Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IP6K2

Antigène: IP6K2 (Inositol Hexakisphosphate Kinase 2 (IP6K2))

Autre désignation: InsP6 Kinase 2 / IP6K2 (IP6K2 Produits)

Synonymes: anticorps IHPK2, anticorps ip6k2, anticorps ihpk2, anticorps cb1087, anticorps wu:fb47g07, anticorps wu:fi24d03, anticorps ihpk2b, anticorps MGC69075, anticorps ihpk2a, anticorps MGC84167, anticorps PIUS, anticorps Ihpk2, anticorps Pius, anticorps 1500005N04Rik, anticorps AW050208, anticorps inositol hexakisphosphate kinase 2, anticorps inositol hexaphosphate kinase 2, anticorps inositol hexakisphosphate kinase 2a, anticorps inositol hexaphosphate kinase 2 L homeolog, anticorps inositol hexakisphosphate kinase 2b, anticorps inositol hexaphosphate kinase 2 S homeolog, anticorps IP6K2, anticorps ip6k2, anticorps ip6k2a, anticorps ip6k2.L, anticorps ip6k2b, anticorps ip6k2.S, anticorps MCYG_02913, anticorps Ip6k2

Sujet: The members of the inositol hexakisphosphate kinase family, IP6K1 and IP6K2, have a high affinity and selectivity for inositol hexakisphosphate (InsP6) as a substrate. IP6K1 and IP6K2 (also designated PiUS) convert InsP6 to PP-InsP5. However, neither kinase demonstrates any catalytic activity with other inositol pyrophosphates. The presence of InsP6, which inhibits serine/threonine protein phosphatases, increases the influx of calcium across the plasma membrane and implies that it may mediate the regulation of insulin exocytosis. IP6K1 was purified as a 54 kDa protein in rat brain extracts. By homology, IP6K1 and IP6K2 were characterized in mouse as a 50 kDa and 49 kDa protein, respectively. IP6K1 displays ATP synthase activity by transferring a phosphate from PP-InsP5 to ADP, which suggests a role for the IP6 kinases as high energy phosphate donors.Synonyms: IHPK2, Inositol hexakisphosphate kinase 2, P(i)-uptake stimulator, PiUS, TCCCIA00113

Poids moléculaire: approx. 52 kDa

ID gène: 51447

NCBI Accession: NP_001005909

UniProt: Q9UHH9