CHRM5 anticorps

N° du produit ABIN317740

Cet anticorps Lapin Polyclonal détecte spécifiquement CHRM5 dans WB et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CHRM5 anticorps (ABIN317740)

Antigène: CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRM5 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-CHRM5 anticorps

Specificité: MAChR M5 antibody detects endogenous levels of mAChR M5 protein.(region surrounding Pro224)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse and Rat.

Purification: Affinity-chromatography

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CHRM5

Antigène: CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))

Autre désignation: Muscarinic Acetylcholine Receptor M5

Sujet: The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain.Synonyms: CHRM5, mAChR M5, mAChR-M5

Poids moléculaire: approx. 45 kDa

ID gène: 1133

NCBI Accession: NP_036257

UniProt: P08912

Pathways: Synaptic Membrane