S1PR3 anticorps

N° du produit ABIN317744

L’anticorps anti-S1PR3 Polyclonal Lapin est utilisé pour la détection de S1PR3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IF et EIA.

Aperçu rapide pour S1PR3 anticorps (ABIN317744)

Antigène: S1PR3 (Sphingosine-1-Phosphate Receptor 3 (S1PR3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp S1PR3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-S1PR3 anticorps

Specificité: This antibody detects endogenous levels of EDG-3 protein.(region surrounding Phe155)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity-chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/40000-1/60000. Wetren blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur S1PR3

Antigène: S1PR3 (Sphingosine-1-Phosphate Receptor 3 (S1PR3))

Autre désignation: EDG-3 / S1P3

Sujet: EDG3 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG3 is sphingosine-1-phosphate. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG3 is expressed in heart, placenta, kidney, and liver tissue.Synonyms: EDG3, Endothelial differentiation G-protein coupled receptor 3, FLJ37523, FLJ93220, LPB3, MGC71696, S1P receptor 3, S1PR3, Sphingosine 1-phosphate receptor 3

Poids moléculaire: approx. 42 kDa

ID gène: 1903

NCBI Accession: NP_005217

UniProt: Q99500