EDG4 anticorps
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- Antigène Voir toutes EDG4 (LPAR2) Anticorps
- EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EDG4 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- EDG-4 antibody detects endogenous levels of EDG-4 protein.(region surrounding Leu310)
- Purification
- Affinity-chromatography
- Top Product
- Discover our top product LPAR2 Anticorps primaire
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- Indications d'application
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
- Autre désignation
- EDG-4 / LPAR2 (LPAR2 Produits)
- Synonymes
- anticorps EDG-4, anticorps EDG4, anticorps LPA-2, anticorps LPA2, anticorps lpa2, anticorps Gpbar1, anticorps Edg4, anticorps IPA2, anticorps Pbx4, anticorps RGD1561336, anticorps zgc:101053, anticorps lysophosphatidic acid receptor 2, anticorps lysophosphatidic acid receptor 2 S homeolog, anticorps G protein-coupled bile acid receptor 1, anticorps growth hormone releasing hormone receptor, anticorps lysophosphatidic acid receptor 2a, anticorps LPAR2, anticorps lpar2.S, anticorps GPBAR1, anticorps Lpar2, anticorps GHRHR, anticorps lpar2a
- Sujet
- The EDG (endothelial differentiation gene) family of G protein coupled receptors consists of eight family members that bind lysophospholipid (LPL) mediators, including sphingosine-1-phosphate (SPP) and lysophosphatidic acid (LPA). EDG-1, EDG-3, EDG-5 (also designated H218 and AGR16) and EDG-8 bind SPP with high-affinity. EDG-6 is a low-affinity receptor for SPP. LPA preferentially binds to EDG-2, EDG-4 and EDG-7. The EDG receptors couple to multiple G proteins to signal through Ras, MAP kinase, Rho, Phospholipase C or other tyrosine kinases, which lead to cell survival, growth, migration and differentiation. EDG-1 signals through Gi proteins to activate Akt and is expressed in glioma cells. EDG-2 is expressed in brain, especially in white matter tract regions, while EDG-3 is expressed in cardiovascular tissue and in cerebellum. EDG-4 is highly expressed on leukocytes and brain, and EDG-5 has wide tissue distribution, including cardiovascular tissue and brain. Expressed in lymphoid and hematopoietic tissues and in lung, EDG-6 signals through Gi/o proteins, which activate growth related pathways.Synonyms: EDG4, Ipa-2, LPAR2, Lysophosphatidic acid receptor 2, Lysophosphatidic acid receptor Edg-4, endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4
- Poids moléculaire
- approx. 39 kDa
- ID gène
- 9170
- NCBI Accession
- NP_004711
- UniProt
- Q9HBW0
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