MC5 Receptor anticorps
Aperçu rapide pour MC5 Receptor anticorps (ABIN317755)
Antigène
Voir toutes MC5 Receptor (MC5R) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- MC5-R antibody detects endogenous levels of MC5-R protein. (region surrounding Glu308)
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Purification
- Affinity chromatography
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Indications d'application
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1,0 mg/mL
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Buffer
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MC5 Receptor (MC5R) (Melanocortin 5 Receptor (MC5R))
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Autre désignation
- MC5-R
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Sujet
- The melanocortin family comprises the α-, β- and γ-melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane, G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.Synonyms: MC-2, MC5R, Melanocortin receptor 5
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Poids moléculaire
- approx. 40 kDa
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ID gène
- 4161
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NCBI Accession
- NP_005904
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UniProt
- P33032
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Pathways
- cAMP Metabolic Process
Antigène
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