PAQR7 anticorps

N° du produit ABIN317756

L’anticorps anti-PAQR7 Polyclonal Lapin est utilisé pour la détection de PAQR7 dans des échantillons de Humain. Il a été validé pour WB et IF.

Aperçu rapide pour PAQR7 anticorps (ABIN317756)

Antigène: PAQR7 (Progestin and AdipoQ Receptor Family Member VII (PAQR7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAQR7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-PAQR7 anticorps

Specificité: MPRα antibody detects endogenous levels of mPRα protein.

Purification: Affinity chormatography

Information d'application

Indications d'application: ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PAQR7

Antigène: PAQR7 (Progestin and AdipoQ Receptor Family Member VII (PAQR7))

Sujet: The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Three distinct groups, designated α, β and γ, comprise this gene family. mPRα, also designated progestin and adipoQ receptor family member VII (PAQR7), consists of an extracellular N-terminus, an intracellular C-terminus, and seven transmembrane domains. It is expressed in ovary, testis, placenta, uterus and bladder. mPRβ, also designated progestin and adipoQ receptor family member VIII (PAQR8), consists of eight putative transmembrane regions and an intracellular N-terminus that contains a leucine-rich motif. It is a 354 amino acid protein with a molecular mass of about 40 kDa and is expressed in brain and spinal cord. Both mPRα and mPRβ may be G protein-coupled receptors and may be involved in oocyte maturation.Synonyms: Membrane progestin receptor alpha, Progestin and adipoQ receptor family member 7, Progestin and adipoQ receptor family member VII, mPR alpha

Poids moléculaire: approx. 40 kDa

ID gène: 164091

NCBI Accession: NP_848509

UniProt: Q86WK9