Melatonin Receptor 1B anticorps

N° du produit ABIN317757

Cet anticorps anti-Melatonin Receptor 1B est un anticorps Lapin Polyclonal détectant Melatonin Receptor 1B dans WB et EIA. Adapté pour Humain.

Aperçu rapide pour Melatonin Receptor 1B anticorps (ABIN317757)

Antigène: Melatonin Receptor 1B (MTNR1B)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Melatonin Receptor 1B est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Melatonin Receptor 1B anticorps

Specificité: This antibody detects endogenous levels of MEL-1B-R protein.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1/1000approx. 1/5000. Western blot: 1/500approx. 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Melatonin Receptor 1B

Antigène: Melatonin Receptor 1B (MTNR1B)

Autre désignation: Melatonin Receptor 1B

Sujet: The melatonin receptors, MEL-1A-R and MEL-1B-R, are members of the superfamily of guanine nucleotide-binding regulatory protein (G protein)-coupled receptors. The melatonin receptors are activated by the hormone melatonin (Mel), which is secreted by the pineal gland at night as part of the circadian clock. MEL-1A-R, a 37 kD protein, is thought to be involved in pacing the biological clock. However, both MEL-1A-R and MEL-1B-R are implicated in controlling cellular growth in response to melatonin. MEL-1B-R is an integral membrane protein expressed in retina and less in brain and hippocampus. Functional studies of NIH/3T3 cells stably expressing the MEL-1B-R melatonin receptor indicate that it is coupled to inhibition of adenylyl cyclase.Synonyms: MTNR1B, Melatonin receptor type 1B

Poids moléculaire: approx. 40 kDa

ID gène: 4544

NCBI Accession: NP_005950

UniProt: P49286