RXFP2 anticorps

N° du produit ABIN317772

Cet anticorps anti-RXFP2 Polyclonal Lapin (ABIN317772) détecte spécifiquement RXFP2 dans WB et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour RXFP2 anticorps (ABIN317772)

Antigène: RXFP2 (Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RXFP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-RXFP2 anticorps

Specificité: This antibody detects endogenous levels of Relaxin Receptor 2 protein.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RXFP2

Antigène: RXFP2 (Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2))

Autre désignation: Relaxin Receptor 2 / RXFP2

Sujet: Relaxins are endocrine and autocrine/paracrine hormones belonging to the insulin gene superfamily. In several mammalian species, relaxin is best known for its role during pregnancy and parturition, when it is produced by the corpora lutea of ovaries and other reproductive tissues. The secretion of relaxin into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. Also, by inhibiting uterine contractions, relaxin may influence the timing of parturition. Two previously characterized orphan receptors designated relaxin receptor 1 (LGR7) and 2 (LGR8) bind relaxin in several tissues, including reproductive tissues, brain, and heart. Upon ligand binding, the relaxin receptors activate adenylate cyclases through Gs proteins. Expression of the relaxin receptors in tissues other than reproductive ones suggests that they have additional physiological functions, such as regulating blood pressure and controlling vascular volume in the heart.Synonyms: G-protein coupled receptor 106, G-protein coupled receptor affecting testicular descent, GPR106, GREAT, LGR8, Leucine-rich repeat-containing G-protein coupled receptor 8, Relaxin family peptide receptor 2

Poids moléculaire: approx. 86 kDa

ID gène: 122042

NCBI Accession: NP_570718

UniProt: Q8WXD0

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction