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CD226 anticorps

CD226 Reactivité: Humain, Souris WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN317787
  • Antigène Voir toutes CD226 Anticorps
    CD226
    Reactivité
    • 72
    • 18
    • 5
    • 4
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 51
    • 23
    • 8
    Lapin
    Clonalité
    • 47
    • 34
    • 1
    Polyclonal
    Conjugué
    • 43
    • 10
    • 9
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD226 est non-conjugé
    Application
    • 42
    • 32
    • 32
    • 16
    • 13
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Specificité
    CD226 antibody detects endogenous levels of CD226 protein.(region surrounding Tyr325)
    Purification
    Affinity chromatography
    Top Product
    Discover our top product CD226 Anticorps primaire
  • Indications d'application
    ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    CD226
    Autre désignation
    CD226 / DNAM1 (CD226 Produits)
    Synonymes
    anticorps CD226, anticorps cd226, anticorps zgc:158817, anticorps BC051526, anticorps DNAM-1, anticorps DNAM1, anticorps Pta1, anticorps TLiSA1, anticorps PTA1, anticorps CD226 molecule, anticorps CD226 antigen, anticorps CD226, anticorps cd226, anticorps Cd226
    Sujet
    CD226 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. CD226 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit Tand NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.Synonyms: DNAM-1, DNAX accessory molecule 1
    Poids moléculaire
    approx. 38 kDa
    ID gène
    10666
    NCBI Accession
    NP_006557
    UniProt
    Q15762
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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