CD226 anticorps

N° du produit ABIN317787

Cet anticorps anti-CD226 Polyclonal Lapin (ABIN317787) détecte spécifiquement CD226 dans WB et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CD226 anticorps (ABIN317787)

Antigène: CD226

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD226 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-CD226 anticorps

Specificité: CD226 antibody detects endogenous levels of CD226 protein.(region surrounding Tyr325)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD226

Antigène: CD226

Autre désignation: CD226 / DNAM1

Sujet: CD226 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. CD226 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit Tand NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.Synonyms: DNAM-1, DNAX accessory molecule 1

Poids moléculaire: approx. 38 kDa

ID gène: 10666

NCBI Accession: NP_006557

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints