RNF144A anticorps

N° du produit ABIN317831

L’anticorps anti-RNF144A Polyclonal Lapin est utilisé pour la détection de RNF144A dans des échantillons de Humain et Souris. Il a été validé pour WB et EIA.

Aperçu rapide pour RNF144A anticorps (ABIN317831)

Antigène: RNF144A (Ring Finger Protein 144A (RNF144A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF144A est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-RNF144A anticorps

Specificité: UBCE7IP4 antibody detects endogenous levels of UBCE7IP4 protein.(region surrounding Arg184)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RNF144A

Antigène: RNF144A (Ring Finger Protein 144A (RNF144A))

Autre désignation: RNF144A / UBCE7IP4

Sujet: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction.The three classes of enzymes involved in ubiquitination are the ubiquitinactivating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). UBCE7IP4 (Ubiquitin-conjugating enzyme 7- interacting protein 4), also known as RNF144A (RING finger protein 144A), KIAA0161 or RNF144, is a 292 amino acid single-pass membrane protein that contains one RING-type zinc finger and two IBR-type zinc fingers. Functioning as an E3 ubiquitin-protein ligase, UBCE7IP4 accepts ubiquitin (in the form of a thioester) from E2 ubiquitin-conjugating enzymes, such as UBC8 and UBCH7, and transfers that ubiquitin residue to target substrates. Via its RING finger, UBCE7IP4 may play a role in protein-DNA and protein-protein interactions throughout the cell.Synonyms: KIAA0161, Probable E3 ubiquitin-protein ligase RNF144A, RING finger protein 144A, RNF144, UbcM4-interacting protein 4, Ubiquitin-conjugating enzyme 7-interacting protein 4, Uip4

Poids moléculaire: approx. 30 kDa

ID gène: 9781

NCBI Accession: NP_055561

UniProt: P50876