ABCC10 anticorps

N° du produit ABIN317845

Détail du produit anti-ABCC10 anticorps

Antigène: ABCC10 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCC10 est non-conjugé

Application: Western Blotting (WB)

Specificité: MRP7 antibody detects endogenous levels of MRP7 protein.(region surrounding Glu865)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ABCC10

Antigène: ABCC10 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10))

Autre désignation: ABCC10 / MRP7 (ABCC10 Produits)

Synonymes: anticorps EST182763, anticorps MRP7, anticorps SIMRP7, anticorps Mrp7, anticorps mFLJ00002, anticorps ATP binding cassette subfamily C member 10, anticorps ATP-binding cassette, sub-family C (CFTR/MRP), member 10, anticorps ABCC10, anticorps Abcc10

Sujet: The MRP family is represented by nine similar ABC transporters that have the ability to transport structurally diverse lipophilic anions and operate as chemical efflux pumps. MRP7 (multidrug resistance-associated protein 7, ATPbinding cassette sub-family C member 10) is a multi-pass membrane protein that belongs to the ABC transporter family (conjugate transporter subfamily). MRP7 is involved with the ATP-dependent transport of 17β-estradiol-D-17-β-glucuronide (E217βG). MRP7 is also probably involved in cellular detoxification through its lipophilic anion extrusion capabilities. MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains. MRP7 likely has three isoforms. Isoform 2 is the most widely expressed, while isoform 1 is predominately expressed in the spleen.Synonyms: ATP-binding cassette, Multidrug resistance-associated protein 7, SIMRP7, member 10, sub-family C

Poids moléculaire: approx. 162 kDa

ID gène: 89845

NCBI Accession: NP_001185863

UniProt: Q5T3U5