QRFPR anticorps

N° du produit ABIN317864

L’anticorps Lapin Polyclonal anti-QRFPR a été validé pour WB, IF et EIA. Il convient pour détecter QRFPR dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour QRFPR anticorps (ABIN317864)

Antigène: QRFPR (Pyroglutamylated RFamide Peptide Receptor (QRFPR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp QRFPR est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-QRFPR anticorps

Specificité: GPR103 antibody detects endogenous levels of GPR 103 protein.(region surrounding Ile310)

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur QRFPR

Antigène: QRFPR (Pyroglutamylated RFamide Peptide Receptor (QRFPR))

Autre désignation: QRFPR / GPR103

Sujet: G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR103 is a 455 amino acid protein with highest expression in the brain, retina, trigeminal ganglion, hypothalamus and vestibular nucleus. In peripheral tissues, GPR103 is expressed only in the heart, kidney and testis. GPR103 may regulate adrenal function. A hypothalamic neuropeptide of the RFamide family (26RFa) acts as an endogenous ligand for GPR103.Synonyms: AQ27, G-protein coupled receptor 103, Orexigenic neuropeptide QRFP receptor, Pyroglutamylated RFamide peptide receptor, SP9155

Poids moléculaire: approx. 49 kDa

ID gène: 84109

NCBI Accession: NP_937822

UniProt: Q96P65