CPN1 anticorps

N° du produit ABIN317900

L’anticorps anti-CPN1 Polyclonal Lapin est utilisé pour la détection de CPN1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour CPN1 anticorps (ABIN317900)

Antigène: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CPN1 anticorps

Specificité: CPN cat antibody detects endogenous levels of CPN cat protein.(region surrounding Gln452)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CPN1

Antigène: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Autre désignation: Carboxypeptidase N Catalytic Chain

Sujet: Carboxypeptidase N (arginine carboxypeptidase or CPN) cleaves basic amino acid residues from the carboxy terminal of peptides and proteins. The enzyme plays a central role in regulating the biologic activity of peptides such as kinins and anaphylatoxins, and therefore is also known as kininase-1 and anaphylatoxin inactivator. CPN is a tetrameric complex consisting of two identical regulatory subunits (CPN reg) and two identical catalytic subunits (CPN cat). The two glycosylated CPN reg subunits protect the two CPN cat subunits and keep them in the circulation. CPN reg is a member of the leucinerich repeat family of proteins and the gene which encodes CPN reg maps to human chromosome 8p22-p23. CPN cat is a member of the regulatory B-type carboxypeptidase group and the gene which encodes CPN cat maps to human chromosome 10.Synonyms: ACBP, Anaphylatoxin inactivator, Arginine carboxypeptidase, CPN, CPN1, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit, Kininase-1, Lysine carboxypeptidase, Plasma carboxypeptidase B, SCPN, Serum carboxypeptidase N

Poids moléculaire: approx. 52 kDa

ID gène: 1369

NCBI Accession: NP_001299

UniProt: P15169

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process