CRABP2 anticorps

N° du produit ABIN317901

Cet anticorps anti-CRABP2 Polyclonal Lapin (ABIN317901) détecte spécifiquement CRABP2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CRABP2 anticorps (ABIN317901)

Antigène: CRABP2 (Cellular Retinoic Acid Binding Protein 2 (CRABP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRABP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CRABP2 anticorps

Specificité: This antibody detects endogenous levels of CRABP-II protein.(region surrounding Pro81)

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CRABP2

Antigène: CRABP2 (Cellular Retinoic Acid Binding Protein 2 (CRABP2))

Autre désignation: CRABP2

Sujet: The cellular retinoic acid-binding protein (CRABP)-I and a related isoform CRABP-II are nuclear receptors for retinoic acid (RA), an important regulator of cell growth and differentiation in fetal and adult tissues. These CRABP proteins mediate the downstream effects of RA in distinct ways. CRABP-I negatively regulates the activity of RA by enhancing the production of RAmetabolizing enzymes and increasing the rate at which RA is degraded. CRABP-II enhances the effects of RA by directly interacting with RA receptors (RAR) and, in turn, promoting the formation of RAR-RA complexes and stimulating RA-mediated gene transcription. Both CRABP-I and CRABP-II are expressed in the embryo, and CRABP-I is ubiquitously expressed in various adult tissues. The expression of CRABP-II is elevated in cells that synthesize relatively large amounts of RA, and it is also predominantly expressed in skin, uterus, ovary, and in the choroid plexus.Synonyms: CRABP-II, Cellular retinoic acid-binding protein 2, Cellular retinoic acid-binding protein II

Poids moléculaire: approx. 16 kDa

ID gène: 1382

NCBI Accession: NP_001186652

UniProt: P29373