KCNK1 anticorps

N° du produit ABIN317929

Cet anticorps Lapin Polyclonal détecte spécifiquement KCNK1 dans WB. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour KCNK1 anticorps (ABIN317929)

Antigène: KCNK1 (Potassium Channel Subfamily K Member 1 (KCNK1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KCNK1 anticorps

Specificité: This antibody detects endogenous levels of TWIK-1 protein.(region surrounding Val322)

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur KCNK1

Antigène: KCNK1 (Potassium Channel Subfamily K Member 1 (KCNK1))

Autre désignation: KCNK1

Sujet: K+ channels are divided into three subclasses, reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions, and include TASK, TREK, TRAAK and TWIK. TWIK-1 mRNA is expressed abundantly in brain and at lower levels in lung, kidney and skeletal muscle. The molecular weight of TWIK-1 in mouse brain is 40 kDa under reducing conditions. TWIK-2 shares low sequence homology with other mammalian family group members, and only 34 % homology with TWIK-1. Human TWIK-2 is expressed in pancreas, placenta and heart, while mouse TWIK-2 is expressed in liver. TWIK-2 is inhibited by intracellular, but not extracellular, acidification.Synonyms: HOHO1, Inward rectifying potassium channel protein TWIK-1, KCNK1, KCNO1, Potassium channel KCNO1, Potassium channel subfamily K member 1, TWIK1

Poids moléculaire: approx. 38 kDa

ID gène: 3775

NCBI Accession: NP_002236

UniProt: O00180