JunB anticorps (pSer259)

N° du produit ABIN318057

Détail du produit anti-JunB anticorps

Antigène: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Épitope: pSer259

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JunB est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of JunB pSer259 protein.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200. Immunoprecipitation: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur JunB

Antigène: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Autre désignation: Jun-B (JUNB Produits)

Synonymes: anticorps AP-1, anticorps junb, anticorps wu:cegs2778, anticorps wu:fa92h07, anticorps wu:fq24h03, anticorps zgc:64066, anticorps MGC81322, anticorps JUNB, anticorps junbl, anticorps wu:fa95h09, anticorps wu:fj44e11, anticorps wu:fj68b07, anticorps zgc:63933, anticorps JunB proto-oncogene, AP-1 transcription factor subunit, anticorps JunB proto-oncogene, AP-1 transcription factor subunit a, anticorps jun B proto-oncogene L homeolog, anticorps jun B proto-oncogene, anticorps jun B proto-oncogene S homeolog, anticorps JunB proto-oncogene, AP-1 transcription factor subunit b, anticorps JUNB, anticorps Junb, anticorps junba, anticorps junb.L, anticorps junb, anticorps junb.S, anticorps junbb

Sujet: The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein along with c-Fos is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.Synonyms: JUNB, Transcription factor jun-B

Poids moléculaire: approx. 38 kDa

ID gène: 3726

NCBI Accession: NP_002220

UniProt: P17275