LIMK2 anticorps (pThr505)

N° du produit ABIN318064

Détail du produit anti-LIMK2 anticorps

Antigène: LIMK2 (LIM Domain Kinase 2 (LIMK2))

Épitope: pThr505

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIMK2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of LIMK2 pThr505 protein.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur LIMK2

Antigène: LIMK2 (LIM Domain Kinase 2 (LIMK2))

Autre désignation: LIMK2 (LIMK2 Produits)

Synonymes: anticorps xlimk2, anticorps zgc:91990, anticorps wu:fa97c09, anticorps wu:fk73e11, anticorps LIMK2, anticorps Limk2b, anticorps Link2, anticorps LIMK, anticorps 9430059K01, anticorps A930024P04Rik, anticorps C85310, anticorps Limk2a, anticorps LIM domain kinase 2 L homeolog, anticorps LIM domain kinase 2, anticorps LIM motif-containing protein kinase 2, anticorps limk2.L, anticorps limk2, anticorps LIMK2, anticorps Limk2

Sujet: Proteins containing LIM motifs are typically involved in cell fate determination and growth control. A family of proteins designated LIM kinases, incuding LIMK-1 and LIMK-2, has been identified. LIMK-1 has been shown to regulate the stabilization of F-Actin structures and Cofilin activity, indicating that LIMK-1 plays a role in a signaling pathway involved in the regulation of cell motility and morpho-genesis. LIMK-1 inhibits neuronal differentiation of PC12 cells, and it is thought to act by interfering with events downstream of MAPK activation. Expression patterns of LIMK-1 and LIMK-2 suggest that these proteins may have different functions during development. A truncated form of LIMK-2 has been identified in adult testis that is thought to arise from an alternative initiation exon.Synonyms: EC=2.7.11.1, LIM domain kinase 2, LIMK-2, LIMK2

Poids moléculaire: approx. 72 kDa

ID gène: 3985

NCBI Accession: NP_005560

UniProt: P53671