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Collagen Type I anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement Collagen Type I dans IHC (fro), IHC (p), IF, RIA et EIA. Il présente une réactivité envers Souris.
N° du produit ABIN318505

Aperçu rapide pour Collagen Type I anticorps (ABIN318505)

Antigène

Voir toutes Collagen Type I (COL1) Anticorps
Collagen Type I (COL1) (Collagen, Type I (COL1))

Reactivité

  • 99
  • 60
  • 56
  • 18
  • 18
  • 17
  • 15
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Souris

Hôte

  • 67
  • 38
  • 13
Lapin

Clonalité

  • 80
  • 38
Polyclonal

Conjugué

  • 59
  • 15
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Cet anticorp Collagen Type I est non-conjugé

Application

  • 78
  • 41
  • 38
  • 34
  • 30
  • 27
  • 26
  • 22
  • 18
  • 17
  • 17
  • 12
  • 11
  • 5
  • 4
  • 3
  • 1
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Radioimmunoassay (RIA), Enzyme Immunoassay (EIA)
  • Specificité

    This antibody is specific for Mouse Collagen type I. Less than 1 % cross reactivity has been observed with Mouse Collagen, types II, VI and III and Human, Chicken and Rat Collagen, type I.

    Purification

    Purified Ig prepared by affinity chromatography

    Immunogène

    Native type I Collagen from Mouse skin.

    Isotype

    IgG
  • Indications d'application

    ELISA: 1/100-1/400. Western Blot. Immunofluorescence: 1/50-1/100. Radioimmunoassays. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: 1/250-1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Phosphate buffered saline containing 0.09 % Sodium Azide as preservative.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    Collagen Type I (COL1) (Collagen, Type I (COL1))

    Autre désignation

    Collagen Type I

    Sujet

    Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.Synonyms: Alpha-1 type I collagen, Alpha-2 type I collagen, COL1A1, COL1A2

    ID gène

    12842

    NCBI Accession

    NP_031768

    UniProt

    P11087
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