Collagen Type I anticorps
Aperçu rapide pour Collagen Type I anticorps (ABIN318505)
Antigène
Voir toutes Collagen Type I (COL1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody is specific for Mouse Collagen type I. Less than 1 % cross reactivity has been observed with Mouse Collagen, types II, VI and III and Human, Chicken and Rat Collagen, type I.
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Purification
- Purified Ig prepared by affinity chromatography
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Immunogène
- Native type I Collagen from Mouse skin.
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Isotype
- IgG
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Indications d'application
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ELISA: 1/100-1/400. Western Blot. Immunofluorescence: 1/50-1/100. Radioimmunoassays. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: 1/250-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Phosphate buffered saline containing 0.09 % Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Collagen Type I (COL1) (Collagen, Type I (COL1))
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Autre désignation
- Collagen Type I
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Sujet
- Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.Synonyms: Alpha-1 type I collagen, Alpha-2 type I collagen, COL1A1, COL1A2
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ID gène
- 12842
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NCBI Accession
- NP_031768
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UniProt
- P11087
Antigène
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