TNNI3 anticorps

N° du produit ABIN318833

L’anticorps anti-TNNI3 Polyclonal Chèvre est utilisé pour la détection de TNNI3 dans des échantillons de Humain. Il a été validé pour EIA.

Aperçu rapide pour TNNI3 anticorps (ABIN318833)

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNI3 est non-conjugé

Application: Enzyme Immunoassay (EIA)

Détail du produit anti-TNNI3 anticorps

Specificité: This antibody recognises human cardiac-specific troponin I, (TnI) an integral inhibitory protein of cardiac muscle which exists as a complex with troponin C (TnC) and troponin T (TnT).

Purification: Purified IgG prepared by Immunoaffinity chromatography

Immunogène: Native human cardiac troponin I, purity greater than 98%.

Isotype: IgG

Information d'application

Indications d'application: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0mg/mL

Buffer: PBS buffer pH 7.4 containing 0.09 % Sodium Azide (NaN3)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TNNI3

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Autre désignation: Cardiac Troponin I

Sujet: The TnT subunit of troponin binds to tropomyosin to form a troponin-tropomyosin complex, anchored in place by the binding of TnI to actin, within muscle thin filaments. Structural change resulting from the binding of calcium to specific sites on the regulatory TnC subunit, releases the inhibitory region of TnI from actin, enabling the attachment of the molecular motor protein myosin, allowing for muscle contraction and hence movement. The measurement of blood TnI and TnT levels is an important diagnostic indicator of heart muscle damage, and can be used to differentiate between angina and myocardic infarction in patients with chest pain. Troponin I has also been shown to inhibit angiogenesis in vivo and in vitro.Synonyms: TNNC1, TNNI3

ID gène: 7137

NCBI Accession: NP_000354

UniProt: P19429