PPARD anticorps (N-Term)

N° du produit ABIN318837

Cet anticorps anti-PPARD Polyclonal Lapin (ABIN318837) détecte spécifiquement PPARD dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Lapin et Singe.

Aperçu rapide pour PPARD anticorps (N-Term) (ABIN318837)

Antigène: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Reactivité: Humain, Souris, Rat, Lapin, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARD est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PPARD anticorps

Épitope: AA 1-14, N-Term

Specificité: This antibody detects peroxisome proliferator-activated receptor, delta (PPARD).

Purification: Purified

Immunogène: Syntetic peptide corresponding to amino acids 1-14 of mouse PPAR delta.

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1: 2000 - 1: 8000. Western Blot: 1: 500 - 1: 2000, detects a band of approximately 55 kDa in heart whole celllysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0mg/mL

Buffer: Phosphate buffered saline pH 7.2 containing 0.01 % Sodium Azide (NaN3)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PPARD

Antigène: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Autre désignation: PPAR-delta

Sujet: PPARD is a member of the nuclear hormone receptor subfamily. Upon activation, PPARD forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARD controls genes involved in lipid metabolism, and enhances fatty acid catabolism and energy uncoupling in adipose tissue and skeletal muscle. PPARD has also been implicated in the proliferation and differentiation of preadipocytes, enterocytes, keratinocytes and the placenta. PPARD agonists could be used therapeutically to target multiple components of the metabolic syndrome, including insulin resistance, hyperglycemia, dyslipidemia, and atherosclerosis.Synonyms: NR1C2, NUCI, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member 2, PPAR-beta, PPARB, PPARD, Peroxisome proliferator-activated receptor delta

ID gène: 19015

NCBI Accession: NP_035275

UniProt: P35396

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation