RNF34 anticorps (N-Term)

N° du produit ABIN318868

Cet anticorps Lapin Polyclonal détecte spécifiquement RNF34 dans WB et EIA. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien et Primate.

Aperçu rapide pour RNF34 anticorps (N-Term) (ABIN318868)

Antigène: RNF34 (Ring Finger Protein 34 (RNF34))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Primate

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF34 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-RNF34 anticorps

Épitope: AA 1-373, N-Term

Specificité: This antibody detects Ring Finger homologous to Inhibitor of apoptosis protein (hRFI).

Purification: Purified

Immunogène: Recombinant protein corresponding to amino acids 1-373 of human RFI.

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1800 - 1: 4000. Western Blot: 1: 100 - 1: 600, detects a band of approximately 42 kDa.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0mg/mL

Buffer: Phosphate buffered saline pH 7.2 containing 0.01 % Sodium Azide (NaN3)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RNF34

Antigène: RNF34 (Ring Finger Protein 34 (RNF34))

Autre désignation: RFI / RNF34

Sujet: RFI is an anti-apoptotic protein which has been shown to be a novel modulator of NF-kB activation, leading to the upregulation of Bcl2 and BclXL. It is also thought to possess E3 ubiquitin protein ligase activity and has been shown to target caspases 8 and 10 for proteasomal degradation. hRFI is expressed ubiquitously, and has been localized to both the nucleus and the cytoplasm. hRFI is also expressed in oesophageal, gastric and colorectal cancers, suggesting a possible association between hRFI and the development of digestive tract cancers.Synonyms: CARP-1, CARP1, Caspases-8 and -10-associated RING finger protein 1, E3 ubiquitin-protein ligase RNF34, FYVE-RING finger protein Momo, Human RING finger homologous to inhibitor of apoptosis protein, RIFF

ID gène: 80196

NCBI Accession: NP_079402

UniProt: Q969K3