DISC1 anticorps (Middle Region)

N° du produit ABIN318901

Détail du produit anti-DISC1 anticorps

Antigène: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Épitope: Middle Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DISC1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificité: This antibody recognises disrupted in schizophrenia 1 (DISC1), 93 kDa protein located in the nucleus, cytoplasm and mitochondria.

Purification: Antisera to human DISC1 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Immunogène: An 18 amino acid peptide located near the centre of human DISC1.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1 - 2g/mL, detects bands of approximately 95100 kDa in SKNSH cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur DISC1

Antigène: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Autre désignation: DISC1 (DISC1 Produits)

Synonymes: anticorps DISC1, anticorps C1orf136, anticorps SCZD9, anticorps disrupted in schizophrenia 1, anticorps disrupted in schizophrenia 1 protein, anticorps disc1, anticorps DISC1, anticorps LOC100580606, anticorps Disc1

Sujet: The DISC1 protein is widely expressed in normal tissues. It is involved in neurite outgrowth and cortical development through its interaction with a variety of proteins including lissencephaly-1 (LIS1), NudeE-like (NUDEL) and phosphodiesterase 4B. In certain cases of schizophrenia the DISC1 gene has been found to be disrupted by a t(1,11) (q42.1,q14.3) translocation, and studies suggest that DISC1 could be a candidate susceptibility gene for this condition.Synonyms: DISC-1, Disrupted in schizophrenia 1 protein, KIAA0457

ID gène: 27185

NCBI Accession: NP_001012975

UniProt: Q9NRI5

Pathways: Regulation of Cell Size