DISC1 anticorps (Middle Region)

N° du produit ABIN318901

Cet anticorps Lapin Polyclonal détecte spécifiquement DISC1 dans WB et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour DISC1 anticorps (Middle Region) (ABIN318901)

Antigène: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DISC1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-DISC1 anticorps

Épitope: Middle Region

Specificité: This antibody recognises disrupted in schizophrenia 1 (DISC1), 93 kDa protein located in the nucleus, cytoplasm and mitochondria.

Purification: Antisera to human DISC1 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Immunogène: An 18 amino acid peptide located near the centre of human DISC1.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1 - 2g/mL, detects bands of approximately 95100 kDa in SKNSH cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur DISC1

Antigène: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Autre désignation: DISC1

Sujet: The DISC1 protein is widely expressed in normal tissues. It is involved in neurite outgrowth and cortical development through its interaction with a variety of proteins including lissencephaly-1 (LIS1), NudeE-like (NUDEL) and phosphodiesterase 4B. In certain cases of schizophrenia the DISC1 gene has been found to be disrupted by a t(1,11) (q42.1,q14.3) translocation, and studies suggest that DISC1 could be a candidate susceptibility gene for this condition.Synonyms: DISC-1, Disrupted in schizophrenia 1 protein, KIAA0457

ID gène: 27185

NCBI Accession: NP_001012975

UniProt: Q9NRI5

Pathways: Regulation of Cell Size