TACR3 anticorps (Middle Region)

N° du produit ABIN318919

Détail du produit anti-TACR3 anticorps

Antigène: TACR3 (Tachykinin Receptor 3 (TACR3))

Épitope: Middle Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TACR3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody recognises TACR3 otherwise known as NK3 Receptor (NK3R), a 52.2 kDa multi-pass membrane protein belonging to the G-protein coupled receptor 1 family. This antibody does not recognise NK1R or NK2R.

Purification: Purified

Immunogène: An 18 amino acid peptide from near the centre of Human TACR3.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections: 5g/mL, requires antigen retrieval using heattreatment prior to staining of paraffin sections. Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 46 kDa in RAW264.7 celllysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur TACR3

Antigène: TACR3 (Tachykinin Receptor 3 (TACR3))

Abstract: TACR3 Produits

Synonymes: anticorps HH11, anticorps NK-3R, anticorps NK3R, anticorps NKR, anticorps TAC3RL, anticorps Nk3r, anticorps Nkr, anticorps Tac3r, anticorps Nmkr, anticorps tachykinin receptor 3, anticorps neuromedin-K receptor, anticorps TACR3, anticorps LOC100544805, anticorps Tacr3

Sujet: TACR3 is a receptor for the tachykinin neuropeptide, neuromedin-k otherwise known as neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei. Following binding of its ligand, NK3R activates a phosphatidylinositol-calcium second messenger system, and it is likely that these signals lead to the release of vasopressin and oxytocin into the circulation. Studies with mice indicate that TACR3 is involved in learning and memory.Synonyms: NK-3 receptor, NK-3R, NK3R, NKR, Neurokinin B receptor, Neuromedin-K receptor, TAC3R

ID gène: 6870

NCBI Accession: NP_001050

UniProt: P29371

Pathways: Feeding Behaviour