Glutamate Receptor 1 anticorps (pSer831)
Aperçu rapide pour Glutamate Receptor 1 anticorps (pSer831) (ABIN319113)
Antigène
Voir toutes Glutamate Receptor 1 (GLUR1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer831
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Specificité
- This antibody is specific for glutamate receptor subunit 1 (GluR1) when phosphorylated at serine 831.
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Purification
- Affinity chromatography
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Immunogène
- Synthetic phosphopeptide corresponding to amino acid sequence within GluR1 which includes phosphorylated Ser831.
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Isotype
- IgG
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Indications d'application
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Western Blot: 1: 1000, detects a band of approximately 100 kDa in rat brain lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Glutamate Receptor 1 (GLUR1)
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Autre désignation
- Glutamate Receptor 1 / GLUR1
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Sujet
- GluR1, widely expressed throughout the nervous system, is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses. Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.Synonyms: AMPA-selective glutamate receptor 1, AMPA1, GLUH1, GRIA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor ionotropic
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ID gène
- 2890
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NCBI Accession
- NP_000818
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UniProt
- P42261
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Pathways
- Signalisation PI3K-Akt
Antigène
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