Tryptophan Hydroxylase 1 anticorps
Aperçu rapide pour Tryptophan Hydroxylase 1 anticorps (ABIN319127)
Antigène
Voir toutes Tryptophan Hydroxylase 1 (TPH1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody recognises Tryptophan Hydroxylase (TPH) which catalyses the 5-hydroxylation of tryptophan, in the first stage of indoleamine biosynthesis. Serotonin biosynthesis occurs principally in neurons which originate in the raphe nucleus of the brain, and melatonin synthesis takes place within the pineal gland.
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Purification
- Affinity chromatography
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Immunogène
- Recombinant rabbit Tryptophan Hydroxylase purified from E. coli.
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Isotype
- IgG
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Indications d'application
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Immunohistochemistry on frozen sections: 1: 1000. Western Blot: 1: 1000, detects a band of approximately 55 kDa in human dorsal Raphenucleus lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Tryptophan Hydroxylase 1 (TPH1)
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Autre désignation
- Tryptophan 5-Hydroxylase 1 (TPH1)
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Sujet
- Synonyms: TPRH, TRPH, Tryptophan 5-monooxygenase 1
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ID gène
- 7166
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NCBI Accession
- NP_004170
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UniProt
- P17752
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Pathways
- Feeding Behaviour
Antigène
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