PPP2CA anticorps (N-Term)

N° du produit ABIN319371

Cet anticorps anti-PPP2CA Polyclonal Lapin (ABIN319371) détecte spécifiquement PPP2CA dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PPP2CA anticorps (N-Term) (ABIN319371)

Antigène: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP2CA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PPP2CA anticorps

Épitope: N-Term

Specificité: PP2A-alpha antibody detects endogenous levels of total PP2A-alpha protein.

Purification: Immunoaffinity Chromatography.

Immunogène: The antiserum was produced against a synthesized peptide Corresponding to the amino terminal sequence from human PP2A-alpha protein (''KQLSESQVKSL'').

Information d'application

Indications d'application: Western Blot (1/500-1/1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at-20 °C.

Détails sur PPP2CA

Antigène: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Autre désignation: PPP2CA

Sujet: Protein phosphatase 2A (PP2A) is the most abundant phosphatase specific for serine and threonine phosphorylation in mammalian cells. Dephosphorylation of substrates targeted by PP2A plays a vital role in a large variety of cellular processes including signal transduction, regulation of the cell cycle, gene expression and development. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit alpha serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory beta subunit.Synonyms: PP2A-alpha, Protein Phospatase 2A, Replication protein C, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

ID gène: 5515

NCBI Accession: NP_002706

UniProt: P67775

Pathways: Signalisation PI3K-Akt, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades