AMBP anticorps
Aperçu rapide pour AMBP anticorps (ABIN319500)
Antigène
Voir toutes AMBP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody recognises human alpha-1-Microglobulin. No cross-reactivity is observed with Urine Albumin, Retinol binding protein or beta-2-Microglobulin. It does Not react with Rat.
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Purification
- Purified IgG prepared by affinity chromatography on Protein G
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Immunogène
- Highly pure human alpha-1-microglobulin, prepared from the urine of patients with chronic renal proteinuria (Molecular Weight 25-30 kD).
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Isotype
- IgG
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Indications d'application
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ELISA (1/500-1/1000). Immunodiffusion.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 5.0 mg/mL
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Buffer
- PBS containing 0.09 % Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- AMBP (alpha 1 Microglobulin/bikunin precursor (AMBP))
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Autre désignation
- AMBP
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Sujet
- Alpha(1)microglobulin/bikunin precursor specifically interacts with the ORF3 protein of hepatitis E virus and has a direct role in enhancing alpha(1)microglobulin export from the hepatocyte. Bikunin has a role in downregulating PI3 kinase and suppressing tumor invasiveness and metastasis in ovaran cancer cells. I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin. Interacts with FN1Synonyms: Alpha-1 microglycoprotein, Alpha-1-microglobulin, Bikunin, Complex-forming glycoprotein heterogeneous in charge, EDC1, HCP, HI-30, ITI-LC, ITIL, Inter-alpha-trypsin inhibitor light chain, Trypstatin, Uronic-acid-rich protein
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ID gène
- 259
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NCBI Accession
- NP_001624
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UniProt
- P02760
Antigène
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