CD16 anticorps

N° du produit ABIN319691

Détail du produit anti-CD16 anticorps

Antigène: CD16

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD16 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificité: This antibody recognizes CD16. This antibody has been reported to block the binding of IgG to the CD16 Molecule. (4)

Purification: Ion Exchange Chromatography

Immunogène: Normal Human peripheral blood granulocytes. Remarks: Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63.653 myeloma cell line.

Clone: LNK16

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: Use 10 μL of 1/10-1/20 diluted antibody to label 10^6 cells or 100 μL human whole blood. Immunoprecipitation. Does not work in Immunohistochemistry on Frozen and Paraffin Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD16

Antigène: CD16

Autre désignation: CD16 (CD16 Produits)

Synonymes: anticorps Fcgr3, anticorps Fcgr3a, anticorps CD16, anticorps FCGR3, anticorps FCGR3@, anticorps CD16b, anticorps FCG3, anticorps FCR-10, anticorps FCRIII, anticorps FCRIIIb, anticorps FcRIII, anticorps Fc fragment of IgG, low affinity IIa, receptor, anticorps Fc fragment of IgG, low affinity IIIa, receptor (CD16a), anticorps Fc fragment of IgG receptor IIIb, anticorps Fc fragment of IgG receptor IIIa, anticorps Fc receptor, IgG, low affinity III, anticorps Fc-gamma RIII, anticorps Fcgr2a, anticorps FCGR3A, anticorps FCGR3B, anticorps Fcgr3, anticorps FCGR3

Sujet: CD16 is a 50-65kD cell surface molecule which exists in two forms, a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A

ID gène: 2214

NCBI Accession: NP_000560

UniProt: P08637

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process