CD52 anticorps

N° du produit ABIN320173

Détail du produit anti-CD52 anticorps

Antigène: CD52

Reactivité: Humain, Singe

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD52 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Cytotoxicity Test (CyTox), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Specificité: SM2135LE reacts with the Human CD52 antigen, also known as CAMPATH-1. Humanised versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies.

Purification: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant

niveau d'endotoxine: Low Endotoxin

Clone: YTH34-5

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry (1/50-1/100): Use 10 μL to label 1 x 10^6 cells in 100 μL. Immunohistochemistry (Frozen/Paraffin/Resin): This product does not require protein digestion pretreatment of paraffin section. However enhanced results may be seen using Trypsin protein digestion (2). ELISA. Western Blotting. Immunoprecipitation. Cytotoxic Assays (50 μg/mL): Use human serum as complement source.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS without preservatives or stabilizers.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD52

Antigène: CD52

Autre désignation: CD52 / CAMPATH-1 (CD52 Produits)

Synonymes: anticorps CD52, anticorps AI463198, anticorps B7, anticorps B7-Ag, anticorps CAMPATH-1, anticorps CLS1, anticorps MB7, anticorps CDW52, anticorps CE5, anticorps CD52 molecule, anticorps CD52 antigen, anticorps CD52, anticorps Cd52

Sujet: The CD52 antigen is a remarkably small peptide that is heavily glycosylated, and attached to the cell surface membrane via a GPI link. The apparent molecular mass of the antigen on SDS-PAGE is 25-29kD. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5

ID gène: 1043

NCBI Accession: NP_001794

UniProt: P31358