CD8 anticorps (FITC)

N° du produit ABIN320305

Cet anticorps Souris Monoclonal détecte spécifiquement CD8 dans FACS. Il présente une réactivité envers Rat.

Aperçu rapide pour CD8 anticorps (FITC) (ABIN320305)

Antigène: CD8

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD8 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: OX-8

Détail du produit anti-CD8 anticorps (FITC)

Specificité: This antibody recognises the CD8 alpha cell surface antigen, expressed by a subset of T lymphocytes, most thymocytes and the majority of NK cells. Clone MRC OX-8 is suitable for use in in vitro blocking studies.

Purification: Ion Exchange Chromatography

Immunogène: Rat thymocyte membrane glycoproteins. Spleen cells from immunised BALB/c mice were fused with cells of the NS1 mouse myeloma cell line.

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: Use 10 μL of Neat-1/10 diluted antibody to label 10^6 cells in 100 μL. This clone has been described reacting with paraffin-embedded material following PLP Fixation (periodatelysine paraformaldehyde).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD8

Antigène: CD8

Autre désignation: CD8

Sujet: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

ID gène: 24930

NCBI Accession: NP_113726

UniProt: P07725