Inhibin alpha anticorps

N° du produit ABIN3210007

Cet anticorps anti-Inhibin alpha Monoclonal Souris (Clone 4A2) (ABIN3210007) détecte spécifiquement Inhibin alpha dans IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Inhibin alpha anticorps (ABIN3210007)

Antigène: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Inhibin alpha est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: 4A2

Détail du produit anti-Inhibin alpha anticorps

Purification: Purified antibody.

Immunogène: Inhibin alpha antibody was raised in Mouse using a purified recombinant fragment of human INHA expressed in E. coli as the immunogen.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10,000, IF: 1:200-1:1000, IHC: 1:200-1:1000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: Purified antibody supplied in PBS containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Détails sur Inhibin alpha

Antigène: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Autre désignation: Inhibin alpha

Sujet: INHA joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Synonyms: Monoclonal Inhibin Alpha antibody, Anti-Inhibin Alpha antibody, INHA antibody.

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion