MUC1 anticorps

N° du produit ABIN3222739

Cet anticorps Souris Monoclonal détecte spécifiquement MUC1 dans IHC (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MUC1 anticorps (ABIN3222739)

Antigène: MUC1 (Mucin 1 (MUC1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-MUC1 anticorps

Specificité: Specific for the tandem repeat of the MUC-1 core. Recognizes the hexapeptide (TRPAPG). The MUC-1 mucin (Cancer Antigen CA15-3) is secreted from tumor cells. The apo-protein of the MUC-1 mucin contains a transmembrane domain, a cytoplasmic domain, and an extracellular carbohydrate rich domain. The extracellular domain is characterized by polymorphism with respect to the number of a 20 amino acid tandem repeat (VNTR polymorphism).

Attributs du produit: Host: Hybridization of P3X63-Ag8.653, myeloma cells with spleen cells from Balb/c mice.

Purification: Purified by Protein A chromatography

Pureté: > 98 % pure

Immunogène: Human breast cancer cell line ZR 75-1

Isotype: IgG1

Information d'application

Indications d'application: Capture or detection antibody in serological assays for the research of antigen MUC-1. Forms a suitable pair withX108 , Catalog # L1C00802. Immunohistochemistry on frozen or paraffin sections for the detection of MUC-1. Immunochemical detection of MUC-1 protein.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1:1000~5000

Buffer: 150mM NaCl 10mM Tris, pH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur MUC1

Antigène: MUC1 (Mucin 1 (MUC1))

Autre désignation: CA15-3

Sujet: Monoclonal Antibody to Carbohydrate Antigen 15-3(CA15-3) (Breast Cancer)

Pathways: Negative Regulation of intrinsic apoptotic Signaling