CEA anticorps

N° du produit ABIN335404

Cet anticorps Souris Monoclonal détecte spécifiquement CEA dans WB, IHC, FACS, IHC (p), ICC et IHC (fro). Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour CEA anticorps (ABIN335404)

Antigène: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: PARLAM 4

Détail du produit anti-CEA anticorps

Specificité: Human.

Immunogène: PARLAM 4 is a mouse monoclonal IgG1 antibody derived by fusion of Sp 2/0 Ag 14 mouse myeloma cells with spleen cells from a BABL/c mouse immunized with isolated human CEA. The immunogen has been isolated from human colonic carcinoma cells.

Isotype: IgG1

Information d'application

Indications d'application: Most polyclonal CEA antisera show cross-reactivity with related antigens such as biliary glycoprotein (BGP) and non-specific cross-reacting antigen 1/11 (NCA). PARLAM 4 does not show cross reactivity, neither with BGP nor with NCA. In immunoblotting the antibody recognizes a single band of 180 kD.

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Références pour anticorps anti-CEA (ABIN335404)

Taal, Hageman, Delemarre, Bonfrèr, den Hartog Jager: "Metastatic ovarian or colonic cancer: a clinical challenge." dans: European journal of cancer (Oxford, England : 1990), Vol. 28, Issue 2-3, pp. 394-9, (1992) (PubMed).

Henzen-Logmans, Schipper, Poels, Stolk, Kenemans, Meyer: "Use of statistical evaluation of antigen profiles in differential diagnosis between colonic and ovarian adenocarcinomas." dans: Journal of clinical pathology, Vol. 41, Issue 6, pp. 644-9, (1988) (PubMed).

Verstijnen, Arends, Moerkerk, Warnaar, Hilgers, Bosman: "CEA-specificity of CEA-reactive monoclonal antibodies. Immunochemical and immunocytochemical studies." dans: Anticancer research, Vol. 6, Issue 1, pp. 97-104, (1986) (PubMed).

Détails sur CEA

Antigène: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Autre désignation: Carcinoembryonic Antigen / CEA

Sujet: This monoclonal antibody is reactive with human carcinoembryonic antigen (CEA), a tumour associated antigen with oncofetal characteristics. Although CEA can be found in tissues of non-neoplastic diseases and normal epithelia, it occurs also in a large variety of carcinomas. Therefore, immunohistochemical detection of CEA is frequently used for the histopathological diagnosis of human tumours.