Smooth Muscle Actin anticorps
Aperçu rapide pour Smooth Muscle Actin anticorps (ABIN336852)
Antigène
Voir toutes Smooth Muscle Actin (ACTA2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Acetyl group with N- terminal four amino acids of peptide chain of alpha smooth muscle.
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Immunogène
- N-terminal decapeptide of alpha smooth muscle isoform of actin, acetylated at the N-terminus
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Isotype
- IgG1
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Indications d'application
- IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections and cell smears. For IHC dilute conc. antibodies 1:50-1:100, use streptavidin-biotin system or polymer system, incubate 30 minutes at room temperature. Prediluted antibody is ready to be used for IHC. The optimum dilution should be determined by the individual lab. Positive Control: Human uterus, gastrointestinal tissue, Leiomyosarcoma. Cellular Localization: Cytoplasmic.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The concentrated antibodies are supplied in PBS with 1% BSA, 0.05% azide, pH 7.4. The Prediluted antibody is supplied in our Universal antibody dilution buffer (AR-6526) green in color.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
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Autre désignation
- a-Actin alpha smooth muscle
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Sujet
- Actin is a globular, roughly 42-kDa protein found in all eukaryotic cells. Actin participates in many important cellular functions, including muscle contraction cell motility cell division and cytokinesis vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape. Expression of smooth muscle alpha actin is regulated by hormones and cell proliferation and is altered by pathological conditions including onogenic transformation and atherosclerosis.
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Pathways
- Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
Antigène
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