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Smooth Muscle Actin anticorps

Cet anticorps anti-Smooth Muscle Actin est un anticorps Souris Monoclonal détectant Smooth Muscle Actin dans IHC et IHC (p). Adapté pour Humain, Rat, Souris, Poulet, Boeuf (Vache) et Babouin.
N° du produit ABIN336852

Aperçu rapide pour Smooth Muscle Actin anticorps (ABIN336852)

Antigène

Voir toutes Smooth Muscle Actin (ACTA2) Anticorps
Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Reactivité

  • 133
  • 87
  • 84
  • 29
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Humain, Rat, Souris, Poulet, Boeuf (Vache), Babouin

Hôte

  • 80
  • 56
  • 1
Souris

Clonalité

  • 93
  • 44
Monoclonal

Conjugué

  • 75
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
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  • 1
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Cet anticorp Smooth Muscle Actin est non-conjugé

Application

  • 74
  • 56
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  • 18
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Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

1A4
  • Specificité

    Acetyl group with N- terminal four amino acids of peptide chain of alpha smooth muscle.

    Immunogène

    N-terminal decapeptide of alpha smooth muscle isoform of actin, acetylated at the N-terminus

    Isotype

    IgG1
  • Indications d'application

    IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections and cell smears. For IHC dilute conc. antibodies 1:50-1:100, use streptavidin-biotin system or polymer system, incubate 30 minutes at room temperature. Prediluted antibody is ready to be used for IHC. The optimum dilution should be determined by the individual lab. Positive Control: Human uterus, gastrointestinal tissue, Leiomyosarcoma. Cellular Localization: Cytoplasmic.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    The concentrated antibodies are supplied in PBS with 1% BSA, 0.05% azide, pH 7.4. The Prediluted antibody is supplied in our Universal antibody dilution buffer (AR-6526) green in color.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C
  • Antigène

    Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

    Autre désignation

    a-Actin alpha smooth muscle

    Sujet

    Actin is a globular, roughly 42-kDa protein found in all eukaryotic cells. Actin participates in many important cellular functions, including muscle contraction cell motility cell division and cytokinesis vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape. Expression of smooth muscle alpha actin is regulated by hormones and cell proliferation and is altered by pathological conditions including onogenic transformation and atherosclerosis.

    Pathways

    Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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