Lactoferrin anticorps
Aperçu rapide pour Lactoferrin anticorps (ABIN337355)
Antigène
Voir toutes Lactoferrin (LTF) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes human lactoferrin, a 78kD globular protein found in body secretions such as milk and saliva and is a member of the transferrin family proteins. Transferrins control the level of free iron in the body, by binding and transporting iron. Lactoferrin does not appear to have a transporting function, instead it has antimicrobial activity, by keeping the levels of iron in body fluids low and thus preventing microbes from acquiring iron. Removing free iron from body fluids and inflamed areas also serve to protect against the damaging effects of free radicals. Lactoferrin is used as a therapeutic and prophylactic treatment of various illnesses, such as cancers and intestinal illnesses. May be used to detect lactoferrin in ELISA assays.
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Purification
- Affinity purified
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Immunogène
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Purified lactoferrin from human milk.
Type of Immunogen: Purified protein -
Isotype
- IgG1
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Indications d'application
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Approved: ELISA, IHC, IHC-P (10 μg/mL), WB
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL. ELISA: May be used in an indirect ELISA or as a detection antibody in a sandwich ELISA together with LS-C58299 as a capture agent. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Lactoferrin (LTF) (Lactotransferrin (LTF))
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Autre désignation
- LF / LTF / Lactoferrin
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Sujet
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Name/Gene ID: LTF
Synonyms: LTF, GIG12, Growth-inhibiting protein 12, HLF2, Lactotransferrin, Lactoferrin, LF, Neutrophil lactoferrin, Talalactoferrin -
ID gène
- 4057
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UniProt
- P02788
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Pathways
- Transition Metal Ion Homeostasis
Antigène
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