PDE11A anticorps (AA 455-468)

N° du produit ABIN337393

Cet anticorps Chèvre Polyclonal détecte spécifiquement PDE11A dans WB, ELISA, IHC et IHC (p). Il présente une réactivité avec des échantillons de Humain, Chien, Boeuf (Vache), Roussette (Chauve-souris), Singe et Porc.

Aperçu rapide pour PDE11A anticorps (AA 455-468) (ABIN337393)

Antigène: PDE11A (phosphodiesterase 11A (PDE11A))

Reactivité: Humain, Chien, Boeuf (Vache), Roussette (Chauve-souris), Singe, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE11A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PDE11A anticorps

Épitope: AA 455-468

Specificité: Human PDE11A. This antibody is expected to recognise all four reported isoforms (NP_058649.3 , NP_001070665.1, NP_001070826.1, NP_001070664.1).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Dog, Bat, Pig (100%) Mouse, Rat, Hamster, Horse, Rabbit, Opossum (93%) Xenopus, Stickleback, Pufferfish, Zebrafish (86%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-NSFKESMEKSSYSD from an internal region of human PDE11A (NP_058649.3 , NP_001070665.1, NP_001070826.1, NP_001070664.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Dog, Bat, Pig (100%), Mouse, Rat, Hamster, Horse, Rabbit, Opossum (93%), Xenopus, Stickleback, Pufferfish, Zebrafish (86%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (10 μg/mL), Peptide-ELISA (1:2000), WB (0.5 - 1.5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur PDE11A

Antigène: PDE11A (phosphodiesterase 11A (PDE11A))

Autre désignation: PDE11A

Sujet: Name/Gene ID: PDE11A
Subfamily: PDE - cAMP/cGMP dual-specific
Family: Phosphodiesterase

Synonyms: PDE11A, Pde11, PDE11A4, PDE11A1, PPNAD2, PDE11A2, PDE11A3, Phosphodiesterase 11A

ID gène: 50940

NCBI Accession: NP_058649, NP_001070665, NP_001070826, NP_001070664

UniProt: Q9HCR9

Pathways: cAMP Metabolic Process