LST1 anticorps

N° du produit ABIN343705

Détail du produit anti-LST1 anticorps

Antigène: LST1 (Leukocyte Specific Transcript 1 (LST1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LST1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificité: The antibody LST1/02 reacts with an extracellular epitope of LST1, an approximately 6-11 kDa protein expressed as various transmembrane or soluble forms. LST1 is found predominantly on monocytes and dendritic cells. It migrates on SDS PAGE gels as approximately 25-28 kDa molecule.

Réactivité croisée (Details): Human, Other not determined

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: KLH-fused peptide corresponding to amino acids SSEGPDLRGRDKRGT of human LST1

Clone: LST1-02

Isotype: IgG1

Information d'application

Indications d'application: Immunoprecipitation: Positive control: RAJI human Burkitt lymphoma cell line.
Western blotting: The antigen migrates on SDS PAGE gels as approximately 25-28 kDa molecule.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur LST1

Antigène: LST1 (Leukocyte Specific Transcript 1 (LST1))

Autre désignation: LST1 (LST1 Produits)

Synonymes: anticorps B144, anticorps D6S49E, anticorps LST-1, anticorps leukocyte specific transcript 1, anticorps LST1, anticorps Lst1

Sujet: Leukocyte specific transcript 1,LST1 (leukocyte-specific transcript 1, also known as B144) is expressed in cells of myeloid/erythroid lineage (monocytes, granulocytes, dendritic cells, platelets, erythrocytes). At least 14 alternatively spliced variants (LST1/A –, LST1/N) can be detected, some of them (LST1/A, B, C, G, I, K) are transmembrane cell surface-exposed forms, the other are soluble. LST1 induces production of long, thin filopodia in dendritic cells, has an inhibitory effect on lymphocyte proliferation and may have an immunomodulatory role. LST1/A is an 11 kDa transmembrane adaptor present in membrane rafts and forms spontaneously covalent homodimers. Its intracellular domain contains two tyrosine motifs, one of them being an ITIM very similar to such motifs in Siglec.,LST-1, B144

ID gène: 7940

UniProt: O00453