AGR3 anticorps
Aperçu rapide pour AGR3 anticorps (ABIN343711)
Antigène
Voir toutes AGR3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Anti-AGR3 Purified
-
Specificité
- The antibody AGR3.1 recognizes the epitope HETTDKNLS within the AGR3 (AG3) protein (19-20 kDa), a secreted cytoplasmic protein which can serve as a marker of carcinogenesis.
-
Réactivité croisée (Details)
- Human, Other species Not tested
-
Purification
- Purified by protein-A affinity chromatography.
-
Pureté
- > 95 % (by SDS-PAGE)
-
Immunogène
- Purified human AGR3 protein
-
Isotype
- IgG1
-
-
-
-
Indications d'application
-
Immunohistochemistry (paraffin sections): Recommended dilution: 1 μg/mL, positive tissue: breast cancer.
Immunohistochemistry (frozen sections): Recommended dilution: 1 μg/mL, positive tissue: breast cancer.
Western blotting: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line.
Immunocytochemistry: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 1 mg/mL
-
Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Do not freeze.
-
Stock
- 4 °C
-
Stockage commentaire
- Store at 2-8°C. Do not freeze.
-
-
- AGR3 (Anterior Gradient 3 (AGR3))
-
Autre désignation
- AGR3
-
Sujet
- Anterior gradient 3, protein disulphide isomerase,AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.,AG3, HAG3
-
ID gène
- 155465
-
UniProt
- Q8TD06
Antigène
-