AGR2+AGR3 anticorps

N° du produit ABIN343713

Cet anticorps anti-AGR2+AGR3 est un anticorps Souris Monoclonal détectant AGR2+AGR3 dans WB, ICC et IHC (p). Adapté pour Humain.

Aperçu rapide pour AGR2+AGR3 anticorps (ABIN343713)

Antigène: AGR2+AGR3

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AGR2+AGR3 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AGR3-4

Détail du produit anti-AGR2+AGR3 anticorps

Fonction: Anti-AGR2/AGR3 Purified

Specificité: The antibody AGR3.4 recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa), secreted cytoplasmic proteins which can serve as markers of carcinogenesis.

Réactivité croisée (Details): Human, Other species Not tested

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Purified human AGR3 protein

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/mL, Positive tissue: human colon.
Western blotting: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line.
Immunocytochemistry: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur AGR2+AGR3

Antigène: AGR2+AGR3

Autre désignation: AGR2/AGR3

Sujet: AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours, AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.,AG2, AG3, HAG2, HAG3